Diffusion Weighted and Diffusion Tensor Imaging: A Clinical by Claudia Leite, Mauricio Castillo

By Claudia Leite, Mauricio Castillo

Diffusion-weighted imaging (DWI) is a vital part of regimen neuroimaging, used approximately universally in mind MRIs, and extra lately for the backbone, spinal wire, and head and neck. DWI offers clinically correct info on stipulations together with stroke, an infection, and neoplasms. Diffusion tensor imaging (DTI) is a robust, more recent method with the potential of a number of protocols, together with the prognosis of gentle irritating mind damage and psychiatric disorders.

Written by means of best professionals in neuroradiology and radiology, Diffusion Weighted and Diffusion Tensor Imaging: A medical Guide presents key issues and summaries at the techniques and functions required for correct implementation and interpretation of DWI and DTI.

Key Features:

  • More than six hundred top of the range illustrations
  • Protocols and purposes from early adolescence to older adulthood
  • Methods to distinguish common as opposed to pathological states
  • Brain edema pathophysiology and use of DWI to differentiate among cytotoxic and vasogenic edema
  • Utilization of DWI and DTI to diagnose trauma, white topic ailment, tumors, cerebrovascular affliction, and head, neck, and backbone disorders

This concise guide is a useful source for neuroradiologists and radiologists, in addition to fellows and citizens in those disciplines. With the increasing use of those systems, neuroscientists, neurologists, neurosurgeons, and psychiatrists also will locate it indispensable.

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Extra info for Diffusion Weighted and Diffusion Tensor Imaging: A Clinical Guide

Example text

Diffusion MRI: what water tells us about the brain. EMBO Mol Med 2014; 6(5): 569–573 [17] Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 1986; 161(2): 401–407 [18] Turner R, Le Bihan D, Maier J, Vavrek R, Hedges LK, Pekar J. Echo-planar imaging of intravoxel incoherent motion. Radiology 1990; 177(2): 407–414 [19] Pipe JG. Motion correction with PROPELLER MRI: application to head motion and free-breathing cardiac imaging.

It is thus recommended that radiologists performing tractography settle on a single acquisition and reconstruction protocol and become familiar with the appearance of tracts that are achieved with this technique. Finally, it is important to emphasize that streamlines in tractography are mathematical entities, not actual fibers, and as such their distribution does not directly correlate with the properties of the underlying axons. For example, the density of the streamlines visualized within a pathway is not directly proportional to the packing density of the neurons within that tract.

MRI reveals swelling of the gray matter and loss of gray–white matter differentiation. 4 Excitotoxicity causes sodium– potassium pump failure and rapid influx of water into the cell. 5 Experimental studies on NMDAtype glutamate receptor antagonists (MK-801) Brain Edema: Pathophysiology Fig. 1 A 42-year-old man with a supratentorial pilocytic astrocytoma with surrounding edema displacing adjacent white matter tracts. (a) T2-fluid=attenuated inversion recovery image showing a well-defined tumor in the right parietal lobe with internal cystic components and layering debris, along with surrounding vasogenic edema (arrow).

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