Basics of PET Imaging: Physics, Chemistry, and Regulations by Gopal B. Saha

By Gopal B. Saha

This reference at the fundamentals of puppy and PET/CT imaging has been revised with concise chapters on puppy basics. The chapters contain pertinent easy technological know-how plus equations in addition to pattern difficulties and perform questions.

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Extra info for Basics of PET Imaging: Physics, Chemistry, and Regulations

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9a) or τ behind (Fig. 9b) the arrival of signal A. As can be seen, they are just touching each other. In these two extreme cases where there is no overlap of the two signals, they will be considered in coincidence and counted as a count. These two scenarios define the minimum limit of coincidence timing window or timing resolution, which is 2τ, twice the width of the time signals. All other coincidence events overlapping within the timing resolution will be counted as coincidence counts (Fig. 9c).

The use of CT scans for attenuation correction reduces the whole-body scan time significantly. CT attenuation correction and fusion of CT and PET images are discussed in detail in Chap. 3. Prior to the introduction of PET/CT, multimodality images were fused by the algorithm technique that was limited mainly to the brain. In 1999, GE Healthcare introduced the first PET/CT, called the Hawkeye, using a dual-head NaI(Tl) camera and a low-energy CT scanner, followed later in 2001 by the Discovery LS (GE Healthcare).

Barium fluoride: Like BGO, BaF2 too does not contain any doping material. 6 ns and is excellent for time-of-flight scanners. In the past its use was limited due to lack of fast computers. With the introduction of fast electronics and computers, they have been used by some investigators for a limited number of clinical studies. Lutetium yttrium oxyorthosilicate: A somewhat new detector, yttrium-activated lutetium oxyorthosilicate (LYSO), has the physical properties similar to LSO and has been used in PET scanners by a commercial vendor.

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