Atlas of Bone Pathology by Shi Wei

By Shi Wei

The Atlas describes and illustrates general and pathologic stipulations afflicting human bone, concentrating on tumor and tumor-like stipulations and their non-neoplastic mimics. Its prime quality electronic pictures are suplemented with radiographic and targeted research photographs.

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There is subtle irregular periosteal reaction as well as lateral cortical destruction. No definite soft tissue mass is identified. The gross features (right) correspond well to the convential radiograph. The tumor is solid, tan-white, and hemorrhagic. Osteosarcoma may arise in any bone of the body but more commonly affects long, tubular bones that contain the most proliferative growth plates, especially those in the distal femur, proximal tibia, and proximal humerus. The favored site within the long bone is the metaphysis, but the tumor also may occur in the diaphysis and, rarely, the epiphysis Fig.

27 Chest wall hamartoma. In this lesion, the cartilage often undergoes endochondral ossification. Note the irregular islets of cartilage. The abundant spicules of osteoid rimmed by plump osteoblasts on the left may result in confusion with chondroblastic osteosarcoma Fig. 28 Chest wall hamartoma. Longstanding lesions typically have mature bone formation 17 18 Fig. 29 Chest wall hamartoma. The solid cartilage components may have intermixed cystic areas filled with blood, thereby resembling an aneurysmal bone cyst Fig.

The radiographic features of osteoblastoma may be specific but more commonly are not, and they may have features suggestive of a malignancy. The margins may be well-demarcated, poorly defined, or indefinite. An osteoblastoma usually does not induce a marked periosteal reaction, as illustrated in this case 30 Fig. 14 Osteoblastoma. Magnetic resonance (MR) images of the lesion shown in Fig. 13. The subchondral epiphyseal lesion is isointense to the adjacent muscle on a T1-weighted sequence (left), with a multilocular brighter and heterogeneous T2 signal (right).

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